Pair Name	Rosmarinic acid, Cisplatin
Disease Info	[ICD-11: 2C73]	Ovarian cancer		Investigative
Biological Phenomena	Inhibition-->Cell migration
Gene Regulation	Down-regulation	Expression	FOXM1	hsa2305
In Vitro Model	SK-OV-3	Ovarian serous cystadenocarcinoma	Homo sapiens (Human)	CVCL_0532
Result	Our research suggests that RAME is a promising option in treating ovarian cancer patients, as it revealed a novel molecular pathway underlying its anti-tumor effects.

Pair Name	Rosmarinic acid, Cisplatin
Disease Info	[ICD-11: 2C25]	Lung cancer		Investigative
Biological Phenomena	Induction-->Blockade of cell cycle in G0/G1 phase
Gene Regulation	Down-regulation	Expression	ABCB1	hsa5243
	Up-regulation	Expression	CDKN1A	hsa1026
	Up-regulation	Activity	MAPK1	hsa5594
	Up-regulation	Expression	TP53	hsa7157
In Vitro Model	A-549	Lung adenocarcinoma	Homo sapiens (Human)	CVCL_0023
In Vivo Model	A549 (3×10⁶) and A549DDP (3×10^6) cells were injected subcutaneously (s.c.) into the flanks of the mice.
Result	Rosmarinic acid reverses non-small cell lung cancer cisplatin resistance by activating the MAPK signaling pathway